Obvious reasons why she will be confirmed. She was first nominated to federal judge by George H.W. Bush. She saved baseball by stopping the player strike years ago. She is also latina. Why is that important? The repubs already have a really bad relationship with the latino community due to attacking immigrants while Bush Jr. was trying to get immigration reform passed last year. (Which did not get passed b/c the repubs squashed it.) They cannot come after her too much for fear of alienating the few latinos still supporting the GOP.
On the face of this, this is a good pick. A lot of experience as a lawyer, trial judge, federal judge, and appeals judge. A very well rounded candidate.